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Klinefelter's Syndrome
Klinefelter's syndrome, 47, XXY or XXY syndrome is a condition caused
by a chromosome aneuploidy. Affected males have an extra X sex
chromosome. The principal effects are development of small testicles and
reduced fertility. A variety of other physical and behavioral
differences and problems are common, though severity varies and many
boys and men with the condition have few detectable symptoms. The second
most common extra chromosome condition, it is named after Dr. Edward
Klinefelter, an endocrinologist at Massachusetts General Hospital,
Boston, Massachusetts, who first described it in 1942 The condition
exists in roughly 1 out of every 500 to 1,000 males.
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